A Deductive Compositional Approach to Petri Nets for Systems Biology

نویسنده

  • Ozan Kahramanoğulları
چکیده

We introduce the language CP, a compositional language for place transition petri nets for the purpose of modelling complex biological systems. The language CP is especially well suited for modelling signalling pathways, where possibly interdependent events with different durations can co-occur. We give the operational semantics of the language CP by means of a proof theoretical deductive system which extends multiplicative exponential linear logic with a self-dual non-commutative logical operator. This makes it possible to compose petri nets at the same level and as nested abstractions, while allowing to do deductive reasoning on the biological systems being modelled by these nets. We demonstrate the use of the language on a model of a signalling pathway for Fc receptor-mediated phagocytosis.

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تاریخ انتشار 2007